Significant Odds Ratios for Driver Impairing Drugs

HIC3	DRUG_NAME	OR	L_OR	U_OR	P-VALUE	A	B	C	D
H2D	BARBITURATES	7.50	2.35	23.91	0.00	10	4499	4	13523
Z2F	MAST CELL STABILIZERS	3.00	1.05	8.55	0.04	7	4502	7	13520
H6C	ANTITUSSIVES,NON-NARCOTIC	2.23	1.30	3.82	0.00	23	4486	31	13496
H3A	ANALGESICS,NARCOTICS	2.22	1.98	2.49	0.00	557	3952	806	12721
H7T	ANTIPSYCHOTICS,ATYPICAL,DOPAMINE,& SEROTONIN ANTAG	2.20	1.37	3.52	0.00	30	4479	41	13486
H6H	SKELETAL MUSCLE RELAXANTS	2.09	1.71	2.55	0.00	167	4342	247	13280
H2F	ANTI-ANXIETY DRUGS	2.00	1.72	2.31	0.00	315	4194	490	13037
H4B	ANTICONVULSANTS	1.97	1.64	2.38	0.00	189	4320	295	13232
H7E	SEROTONIN-2 ANTAGONIST/REUPTAKE INHIBITORS (SARIS)	1.90	1.49	2.44	0.00	105	4404	167	13360
J2A	BELLADONNA ALKALOIDS	1.85	1.08	3.19	0.03	21	4488	34	13493
C4G	INSULINS	1.80	1.45	2.22	0.00	140	4369	237	13290
A4B	HYPOTENSIVES,SYMPATHOLYTIC	1.79	1.17	2.74	0.01	34	4475	57	13470
H7C	SEROTONIN-NOREPINEPHRINE REUPTAKE-INHIB (SNRIS)	1.78	1.19	2.66	0.00	38	4471	64	13463
M9P	PLATELET AGGREGATION INHIBITORS	1.69	1.17	2.43	0.01	46	4463	83	13444
H6J	ANTIEMETIC/ANTIVERTIGO AGENTS	1.63	1.17	2.28	0.00	54	4455	100	13427
H6A	ANTIPARKINSONISM DRUGS,OTHER	1.62	0.99	2.66	0.05	25	4484	47	13480
B3K	COUGH AND/OR COLD PREPARATIONS	1.62	1.19	2.20	0.00	63	4446	118	13409
H2S	SEROTONIN SPECIFIC REUPTAKE INHIBITOR (SSRIS)	1.59	1.40	1.81	0.00	380	4129	741	12786
B3J	EXPECTORANTS	1.58	1.28	1.94	0.00	142	4367	275	13252
S2B	NSAIDS, CYCLOOXYGENASE INHIBITOR - TYPE	1.58	1.41	1.76	0.00	534	3975	1066	12461
Z2A	ANTIHISTAMINES	1.55	1.36	1.78	0.00	349	4160	693	12834
D4K	GASTRIC ACID SECRETION REDUCERS	1.55	1.38	1.73	0.00	491	4018	995	12532
C4K	HYPOGLYCEMICS, INSULIN-RELEASE STIMULANT TYPE	1.50	1.28	1.76	0.00	238	4271	486	13041
C4L	HYPOGLYCEMICS, BIGUANIDE TYPE (NON-SULFONYLUREAS)	1.49	1.23	1.80	0.00	169	4340	345	13182
H2E	SEDATIVE-HYPNOTICS,NON-BARBITURATE	1.48	1.16	1.88	0.00	100	4409	206	13321
H2U	TRICYCLIC ANTIDEPRESSANTS & REL. NON-SEL. RU-INHIB	1.41	1.15	1.73	0.00	139	4370	300	13227
J5D	BETA-ADRENERGIC AGENTS	1.35	1.12	1.64	0.00	157	4352	352	13175
C4N	HYPOGLYCEMICS, INSULIN-RESPONSE ENHANCER (N-S)	1.35	1.01	1.80	0.04	68	4441	152	13375
R1M	LOOP DIURETICS	1.35	1.10	1.65	0.00	136	4373	306	13221
R1L	POTASSIUM SPARING DIURETICS IN COMBINATION	1.33	1.10	1.61	0.00	161	4348	366	13161
A7B	VASODILATORS,CORONARY	1.31	1.04	1.66	0.02	103	4406	237	13290
M9L	ORAL ANTICOAGULANTS,COUMARIN TYPE	1.31	1.01	1.70	0.04	84	4425	193	13334
P3A	THYROID HORMONES	1.29	1.12	1.48	0.00	307	4202	730	12797
A9A	CALCIUM CHANNEL BLOCKING AGENTS	1.25	1.10	1.41	0.00	401	4108	985	12542
A4D	HYPOTENSIVES, ACE INHIBITORS	1.23	1.11	1.37	0.00	534	3975	1330	12197

Leroy A, Morse MM.APPENDIX VIII. Table 1B Significant Odds Ratios for Driver Impairing Drugs.US Department of Transportation/National Highway Traffic Safety Administration. Exploratory study of the relationship between multiple medications and vehicle crashes: analysis of databases. Washington, DC: U.S.DOT/NHTSA; 2008: Publication DTNH22-02-C-05075. P210 May, 2008.
https://www.nhtsa.gov/sites/nhtsa.dot.gov/files/810858.pdf